Download Citation on ResearchGate | Chromosome Philadelphie | Two examples of Philadelphia chromosomes in chronic granulocytic leukemia are reported. Download Citation on ResearchGate | Le chromosome Philadelphie est un dérivé du chromosome 22, marqueur de la leucémie myéloïde chronique (LMC). Leucémie aiguë lymphoblastique à chromosome Philadelphie: aspects moléculaires Volume 6, supplement 1, Supplément, Janvier-Février Print; Save to.
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The fusion of the abl oncogene with the bcr gene which results from this translocation can also be detected by molecular analysis.
Leucémie myéloïde chronique (LMC)
A good correlation is observed between cytogenetic and FISH results in patients at diagnosis or under treatment. However dyscrepancies between the results of these two techniques must be considered. FISH is usefull for detecting cryptic or variant translocations, or for assessing the remission rate when cytogenetics is unsuccesfull. The need of quantitative methods is evident, but technical problems in standardization limits its application for residual disease evaluation.
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Leucémie myéloïde chronique (LMC) · Groupe québécois de recherche en LMC-NMP
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