Frey syndrome is characterized by unilateral flushing and sweating of the facial skin innervated by the auriculotemporal nerve (neck, parotid region, and. A neurologist from Poland, Dr. Lucja Frey, provided a detailed assessment of the disorder and coined the term “auriculotemporal syndrome” in Auriculotemporal nerve syndrome, also known as Frey syndrome, is an uncommon clinical entity in children. It is widely thought to be the result.

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Diagnosis of Frey syndrome is based on clinical history, but confirmatory testing can be done with a Minor starch-iodine test.

Auriculotemppral times children are misdiagnosed as having food allergy and subjected to unnecessary skin prick tests or blood tests for allergy. In Frey syndrome, researchers believe that the parasympathetic and sympathetic nerves near the parotid glands are cut, especially tiny branches originating from the auriculotemporal nerve.

Generally, the symptoms are mild but can result in discomfort as well as social anxiety and avoidance. See other articles in PMC that cite the published article. MotzMD and Young J.

Auriculotemporal Syndrome (Frey Syndrome) — Johns Hopkins University

Treatment of postparotidectomy Frey syndrome with the interposition of temporalis fascia and sternocleidomastoid flaps. Open in a separate window. Pathophysiology Frey syndrome is due to the misdirected regenerative process of the auriculotemporal nerve. Introduction The disorder was first reported in the medical literature by Baillarger in The publisher’s final edited version of this article is available at Otolaryngol Clin North Am.

Frey syndrome is due to the misdirected regenerative process of the auriculotemporal nerve. Pain is sometimes described, but it is probably more related to the surgery than actually to Frey syndrome.

What is the Cause of the Disease? Parasympathetic nerves are part of the autonomic nervous system, which is the portion of the nerve system that controls or regulates involuntary body functions i. An unusual variant presenting as gustatory flushing mimicking food allergy”. All the treatment options have been used with variable success rates. The exact incidence of Frey syndrome is unknown.

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Previous studies have demonstrated that patients undergoing BTA injection demonstrate improvement in symptoms of gustatory sweating and flushing. For more information on this disorder, choose the specific disorder name as your search term in the Rare Disease Database. Most of the therapies used are given via injection therapy or by topical application. Frey syndrome is a rare disorder that most often occurs as a result of surgery in the area near the parotid glands.

In addition, ADM represents a suitable alternative to local fascia and muscle flaps for the prevention ahriculotemporal Frey syndrome. Powered By Decision Support in Medicine. Although the exact percentage is not agreed upon in the medical literature, some sources suggest that more than half of all individuals who undergo aruiculotemporal parotidectomy eventually develop Frey syndrome.

Temporomandibular joints auriculoteemporal, muscles of mastication and malocclusions — Jaw joints, chewing muscles and bite abnormalities Bruxism Condylar resorption Mandibular dislocation Malocclusion Crossbite Open bite Overbite Overeruption Auriculotmeporal Prognathia Retrognathia Scissor bite Maxillary hypoplasia Temporomandibular joint dysfunction.

Please help improve this article by adding citations to reliable sources. Synonyms of Frey Syndrome auriculotermporal syndrome gustatory sweating. The therapy consists of local injections of botulinum A toxin in the affected skin.

Additional symptoms that may be associated with Frey syndrome include flushing and warmth in the affected areas. Superficial musculoaponeurotic system flap Another technique, focused on creating a physical barrier between the underlying regenerating auriculotemporal nerve fibers and the overlying dermis, is a superficial musculoaponeurotic system SMAS flap.

Lucja Frey, provided a detailed assessment of the disorder and coined the term “auriculotemporal syndrome” in The treatment is only supportive.

Auriculotemporal nerve syndrome / Frey syndrome/Gustatory sweating

By using this site, you agree to the Terms of Use and Privacy Policy. Surgical removal excision of the affected skin and the insertion interposition of new tissue to the affected area muscle flaps has been described, but are considered risky because of the presence of facial nerve fibers right below the skin after parotidectomy.

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This may occur consistently with every solid food feeding. National Institutes of Health.

Create a free personal account to access your subscriptions, sign up for alerts, and more. When sweat reacts with iodine, it turns the starch brown.

AU – Kim, Young J. The most common reported cause of Frey syndrome is a surgical procedure called a parotidectomy the surgical removal of a parotid gland. December Learn how and when to remove this template message. Orofacial soft tissues — Soft tissues around the mouth Actinomycosis Angioedema Basal cell carcinoma Cutaneous sinus of dental origin Cystic hygroma Gnathophyma Ludwig’s angina Macrostomia Melkersson—Rosenthal syndrome Microstomia Noma Oral Crohn’s disease Orofacial granulomatosis Perioral dermatitis Pyostomatitis vegetans.

Br J Oral Maxillofac Surg.

Basal cell adenoma Canalicular adenoma Ductal papilloma Monomorphic adenoma Myoepithelioma Oncocytoma Papillary cystadenoma lymphomatosum Pleomorphic adenoma Sebaceous adenoma Malignant: In other cases, such as those that experience profuse sweating, affected individuals may require therapy. Transposition Muscle or Fascia Flaps Similar to increasing the thickness of the elevated skin flap to shield the facial sweat glands from aberrant reinnervation, pedicled muscle and fascia flaps have been used to cover the resected parotid gland in an attempt to create a physical barrier between the overlying dermis and the transected nerve auuriculotemporal within the parotid.

Sign in to download free article PDFs Sign in to access your subscriptions Sign in to your personal account. Symptoms of the following disorders can be similar to those of Frey syndrome. Author manuscript; available in PMC Jun 4. Temporomandibular jointsmuscles of mastication and malocclusions — Jaw joints, chewing muscles and bite abnormalities.

Br J Plast Surg. Sign in to access your subscriptions Sign in to your personal account. A wide variety of conditions can cause profuse sweating as a symptom. Springer, New York, NY; Frey syndrome, Gustatory sweating, Parotidectomy, Botulinum A toxin.